LL-37 Peptide 5mg

LL-37 is a human antimicrobial peptide (AMP) and part of the innate immune system. It is the only known human member of the cathelicidin family of peptides. ll-37 peptide buy​

Key facts

• Full name: Leucine-Leucine-37 (named because it starts with two leucines and contains 37 amino acids)
• Gene source: Produced from the human CAMP gene
• Main role: Helps defend against bacteria, viruses, fungi, and some parasites
• Produced by: Neutrophils, epithelial cells, macrophages, and skin cells

Biological functions

LL-37 has several important activities:

1. Direct antimicrobial action
   • Disrupts microbial membranes
   • Can kill Gram-positive and Gram-negative bacteria
2. Immune modulation
   • Recruits immune cells
   • Influences inflammation and cytokine release
3. Wound healing
   • Promotes tissue repair
   • Stimulates angiogenesis
4. Biofilm disruption
   • Can interfere with bacterial biofilms

Structure

LL-37 is an α-helical cationic peptide, meaning:

• Positively charged
• Amphipathic (has both hydrophobic and hydrophilic sides)

This allows it to interact strongly with negatively charged microbial membranes.

Clinical and research interest for LL-37 Peptide 5mg

LL-37 is being studied for:

• Antibiotic-resistant infections
• Chronic wounds
• Autoimmune diseases like psoriasis and lupus
• Cancer biology
• Potential therapeutic peptide development

Important caution

Although LL-37 has antimicrobial properties, it is not an approved general-use therapeutic peptide for self-medication. Experimental or compounded peptide products marketed online may have uncertain purity, dosing, and safety.

Potential Research Applications for LL-37 Peptide

1. Antimicrobial and Immunomodulatory Studies

• LL-37 is a potent antimicrobial peptide that has been used to investigate its activity against a wide range of pathogens, including bacteria, viruses, and fungi. It also plays a role in modulating the immune response, making it a valuable tool in research on infectious diseases and inflammation [1].

2. Wound Healing and Tissue Regeneration

• Researchers utilize LL-37 to study its effects on wound repair and tissue regeneration. Its ability to promote cell migration and angiogenesis makes it a promising candidate for developing novel therapies for chronic wounds and tissue injuries [2].

3. Inflammatory and Autoimmune Conditions

• The immunomodulatory properties of LL-37 are under investigation for their potential to regulate inflammatory pathways and immune cell activity. This research is critical for understanding autoimmune disorders and developing peptide-based anti-inflammatory strategies [3].

4. Cancer Research

• Preliminary studies suggest that LL-37 may influence tumor microenvironments by modulating immune responses and affecting cell proliferation. Researchers are exploring its dual role in both tumor suppression and promotion in different cancer models.

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